Tuesday, March 18, 2014
Monday, February 17, 2014
Mapping a Living Brain, Neuron by Neuron
Too cool not to share.
Rich Pollett originally shared:
Mapping a Living Brain, Neuron by Neuron
It looks like an oddly shaped campfire, but it is activity of individual neurons across a larval fish brain. It is the first time that researchers have been able to image an entire vertebrate brain at the level of single cells.
Brain function relies on communication between large populations of neurons across multiple brain areas, a full understanding of which would require knowledge of the time-varying activity of all neurons in the central nervous system. Here we use light-sheet microscopy to record activity, reported through the genetically encoded calcium indicator GCaMP5G, from the entire volume of the brain of the larval zebrafish in vivo at 0.8 Hz, capturing more than 80% of all neurons at single-cell resolution. Demonstrating how this technique can be used to reveal functionally defined circuits across the brain, we identify two populations of neurons with correlated activity patterns. One circuit consists of hindbrain neurons functionally coupled to spinal cord neuropil. The other consists of an anatomically symmetric population in the anterior hindbrain, with activity in the left and right halves oscillating in antiphase, on a timescale of 20 s, and coupled to equally slow oscillations in the inferior olive.
NATURE Methods | Article:
http://ift.tt/YEfk19
Video Nature: nmeth.2434_video_s4
Brain Activity Map Project: http://ift.tt/101TGWP
.
via Marlow Weston - Google+ Posts http://ift.tt/1fuacIw
Rich Pollett originally shared:
Mapping a Living Brain, Neuron by Neuron
It looks like an oddly shaped campfire, but it is activity of individual neurons across a larval fish brain. It is the first time that researchers have been able to image an entire vertebrate brain at the level of single cells.
Brain function relies on communication between large populations of neurons across multiple brain areas, a full understanding of which would require knowledge of the time-varying activity of all neurons in the central nervous system. Here we use light-sheet microscopy to record activity, reported through the genetically encoded calcium indicator GCaMP5G, from the entire volume of the brain of the larval zebrafish in vivo at 0.8 Hz, capturing more than 80% of all neurons at single-cell resolution. Demonstrating how this technique can be used to reveal functionally defined circuits across the brain, we identify two populations of neurons with correlated activity patterns. One circuit consists of hindbrain neurons functionally coupled to spinal cord neuropil. The other consists of an anatomically symmetric population in the anterior hindbrain, with activity in the left and right halves oscillating in antiphase, on a timescale of 20 s, and coupled to equally slow oscillations in the inferior olive.
NATURE Methods | Article:
http://ift.tt/YEfk19
Video Nature: nmeth.2434_video_s4
Brain Activity Map Project: http://ift.tt/101TGWP
.
via Marlow Weston - Google+ Posts http://ift.tt/1fuacIw
Twinkle, Twinkle Musical Star
Twinkle, Twinkle Musical Star Early musical nurturing spreads a wide creative ripple through life. |
via Marlow Weston - Google+ Posts http://ift.tt/1fuafEa
Intro to Static Trapeze
Intro to Static Trapeze
Sunday February 10th, 12pm-2pm
@ Albuquerque Aerialist Collective, 1715 5th St NW Albuquerque, New Mexico 87102
Have you wanted to try static trapeze and never had the chance? Trapeze newbies, this class is for you!
We'll do a quick warm up on the ground, some injury prevention exercises for the shoulders and learn skills in the air on the static trapeze.
Prerequisite: Be in a healthy place with your shoulders; no previous aerial experience necessary.
$35, pre-registration and payment required, contact Marlow: catblade@gmail.com to register
maximum # of students: 6
via Marlow Weston - Google+ Posts http://ift.tt/1fuabV4
Sunday February 10th, 12pm-2pm
@ Albuquerque Aerialist Collective, 1715 5th St NW Albuquerque, New Mexico 87102
Have you wanted to try static trapeze and never had the chance? Trapeze newbies, this class is for you!
We'll do a quick warm up on the ground, some injury prevention exercises for the shoulders and learn skills in the air on the static trapeze.
Prerequisite: Be in a healthy place with your shoulders; no previous aerial experience necessary.
$35, pre-registration and payment required, contact Marlow: catblade@gmail.com to register
maximum # of students: 6
via Marlow Weston - Google+ Posts http://ift.tt/1fuabV4
Friday, February 14, 2014
Reasons My Son Is Crying
Reasons My Son Is Crying We put this pillow behind his head so he didn't hurt himself on the window frame. 6 hours ago · 849 notes · I wouldn’t let him drink bath water. I wouldn't let him drink bath water. 17 hours ago · 178... |
via Marlow Weston - Google+ Posts http://ift.tt/1cHp4jc
Sunday, February 9, 2014
It's been a long week. I'd like to post something to inspire you to go out and do amazing things but...
It's been a long week. I'd like to post something to inspire you to go out and do amazing things but my brain really isn't working. So instead, you get this....
Have a great weekend G+! :)
via Marlow Weston - Google+ Posts http://ift.tt/1llLNHl
Have a great weekend G+! :)
via Marlow Weston - Google+ Posts http://ift.tt/1llLNHl
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